The most common cancer pain is the most basic method shall be drug therapy. Drug therapy is effective, markedly fast, safe and economical. However, there are still many doctors do not understand the pain of cancer patients drugs, such as a survey of patients with moderate to severe pain, pain treatment, there are 13.25% of non-cancer medical professionals first use clonidine.
Cancer pain medication should follow the principle of three-step
Di director, said the World Health Organization’s cancer pain drug treatment medication three step principle, stressed by step drug; oral administration; time taking the medication; individual administration; attention to details. Delivery is by ladder from weak to strong, gradually increase the amount of such patient had not only available, but a regular medication schedule. Adhere to the principle of individuation is not the so-called “very content” restrictions, and to achieve an effective analgesic for the purpose.
He said the hospital Professor Liu Shujun and other applications in the long-term pain management summarized some attention, such as dosage regimens should be simple and minimal pain relief trauma therapy began; the best oral, if not rectal or oral administration should consider the subcutaneous administration; Do not use a placebo treatment of cancer pain, with placebo and not really pain, this patient is cruel; on opioids, different adverse reactions on the sensitivity of the patient are very different, application to pay attention; patients pain after discharge should be given a written treatment plan.
Three-step analgesic commonly used drugs which
Non-steroidal anti-inflammatory drugs for mild pain, commonly used drugs are aspirin, acetaminophen, ibuprofen, indomethacin and so on.
Moderate pain on weak opioids can be used, such as codeine and so on.
With severe pain can be strong opioid such as morphine, sustained-release morphine, Duragesic so.
Cancer Pain Relief Do not use meperidine and dihydro-Ai Tuofei
Di Li Jun, director, said the analgesic effects of morphine clonidine 1 / 8, analgesia can only maintain two and a half hours to three and a half hours. Metabolism of the drug in the body to a pethidine, it has a central nervous system toxicity, cancer patients after high-dose use of this drug will definitely lead to accumulation of intoxication, there may be tremors, hallucinations, seizures, myoclonus and epilepsy . Therefore, clonidine may be used only short-term pain relief of acute pain. Long-term use can lead to significant dihydro Ai Tuofei psychological dependence and physical dependence can not be used for routine treatment of cancer pain.
Used opioid in cancer pain without fear of addiction Di director, said many patients and doctors are worried that applications will appear opioid addiction, in fact, such worries are unnecessary.The so-called addiction is psychological dependence, then patients will not help and unscrupulous desire to obtain drugs, often to the detriment of health and family happiness for the expense of drugs. 10,000 applications have one pair of opioid analgesics for cancer patients in the survey show that in these patients is not a mental dependence. A second study of 11 882 application of opioid analgesics for cancer patients to a survey, only four patients in mental dependence. Therefore, the patient need not worry about addiction. In the application of opioid physical dependence and tolerance when it is normal pharmacology of the phenomenon, should not affect drugs
Objects continue to use. Di director cautions, long-term application of opioids, particularly its resistant patients, because of the opioid antagonist is very sensitive to respiratory depression was corrected in a very vulnerable to severe withdrawal symptoms and pain recurrence.
Most patients will get rid of standard pain medication
Some patients think that I no use of analgesic injections, you let me take a few pills will work?Di Director introduced, the kind that the poor oral analgesic effect, pain is not the concept of time is not right. The results show that, according to a three-tiered administration principles, 80% to 90% of cancer patients in pain relief, rather than standard analgesic effect not only bad medicine, but the proportion of adverse events was also high. So who can be treated by oral administration of oral medication as possible. After specification of other drugs could not be effective after the relief of pain patients, can other methods. Di director said that with the progress of pain research, now is not this part of the patient can do nothing.
Fortunately, this pain can be used in patients with adjuvant therapy capsule will definitely help ease the pain.
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May 13th, 2010
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